Applying solitary-molecule optical and AFM imaging and power-spectroscopy methods, we look for to unravel the mechanistic aspects of the framework and dynamics of chromosomes. Our analysis interests involve:
1996, 1st mesoscopic demand density waves devices; and 1st electrical measurements on a single steel nanocluster involving nanoelectrodes
Multicolor imaging in the bacterial nucleoid and cell division proteins with blue, orange, and in the vicinity of-infrared fluorescent proteins
Because 2000, Dekker has shifted the leading focus of his perform to biophysics where he reports the Attributes of single biomolecules and cells using the equipment of nanotechnology. This modification of industry was driven by his fascination to the amazing performing of biological molecular structures, along with with the extensive-time period perspective that a lot of intriguing discoveries is often predicted During this industry.[five] Present-day lines of research in his biophysics group are within the regions of:[six]
2012, discovery that nucleoid occlusion underlies the accuracy of bacterial mobile division; and initial at any time research of your dynamics DNA supercoils and the invention of supercoil hopping
Immediate immobilization of native yeast iso-1 cytochrome c on bare gold: fast electron relay to redox enzymes and zeptomole protein-film voltammetry
MATLAB codes for information processing are offered at . Julia codes utilized for numerical simulation are available at .
Movement-pushed rotary motors for instance windmills and water wheels drive practical processes in human Culture. While samples of these types of rotary motors also function prominently in cell biology, their synthetic development for the nanoscale has remained challenging. Here we show movement-driven rotary motion of a self-organized DNA nanostructure which is docked onto a nanopore in a thin sound-condition membrane. An elastic DNA bundle self-assembles into a chiral conformation upon phoretic docking onto the strong-state nanopore, and subsequently displays a sustained unidirectional rotary movement of up to twenty rev s−one.
2003, demonstrated the first biosensors made outside of a carbon nanotube; solved the construction and mechanism of DNA repair proteins; and discovery of a completely new system for fabricating good-condition nanopores for DNA translocation
It absolutely was all through this period that Dekker carried out study on magnetic spin techniques and on sound in superconductors and semiconductors.
‘The concept that There may be this kind of factor like a beginning, a huge bang, is previously an interesting signpost to contemplate that there was a creator. But additional commonly, and on The premise of pure rationality, I also arrive in a Christian interpretation of actuality. An atheistic worldview is often a naturalistic worldview: basically, you will find only atoms and organic forces that we could evaluate.
Afterwards we spoke yet again briefly for the reason that Dekker felt that our discussion of his faith swiftly grew to become purely philosophical, While In addition it concretely helps him in his perform.
Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of one wire bridging two electrodes
The biophysicist from Delft – who is Probably the most cited scientists during the Netherlands For some time – normally takes his https://www.ceesdekker.net duty to contribute into the rationalization and popularisation of his operate on the border of physics and biology very seriously and on a regular basis seems inside the media; if not to look at his operate, then about the relationship concerning science and his Christian religion.